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KMID : 0383820120730020115
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Tuberculosis and Respiratory Diseases
2012 Volume.73 No. 2 p.115 ~ p.121
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A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis
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Park Ki-Hoon
Kwon Soon-Seog
Chung Myung-Hee
Kim Jae-Na
Lee Hee-Jung
Min Ji-Won
Kim Yong-Hyun
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Abstract
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Conclusion: Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic pulmonary lymphoproliferative disorder, such as lymphocytic interstitial pneumonitis (LIP). A recent estimate predicts that less than 5% of LIP patients acquire malignant, low-grade, B-cell lymphoma. In Korea, there has been no previous report of malignant low-grade, B-cell lymphoma, acquired from LIP. Here, we present the case of a patient with LIP that developed into pulmonary MALT lymphoma, six years after diagnosis.
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KEYWORD
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Lymphoma, Lymphoproliferative Disorders, Lung Diseases, Interstitial, Lymphoid Tissue
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